教師基本信息
職稱:副研究員,博士生導師
電子郵箱:fengqian@fudan.edu.cn
辦公地點:複旦大學生命科學學院C621
辦公電話:021-31246623
個人簡介
男,副研究員,博士生導師,上海國際人類表型組研究院免疫表型組研究所副所長。2005年於華東理工大學獲得博士學位,後於美國耶魯大學從事博士後及助理科學家研究。2013年回國就職於複旦大學生命科學院,2019年進入複旦大學人類表型組研究院,主攻免疫表型組學研究。
研究方向
²免疫表型組學新技術新方法開發及免疫量化評估的應用
²人體免疫係統多樣性及免疫病理生理特征研究(免疫衰老、腫瘤免疫、免疫性疾病)
²微生物與宿主的免疫互作及機製研究
代表性論文和論著
1. Chen Y, Zheng Y, Yu Y, Wang Y, Huang Q, Qian F (Co-first author), Sun L, Song Z, Chen Z, Feng J, An Y, Yang J, Su Z, Sun S, Dai F, Chen Q, Lu Q, Li P, Ling Y, Yang Z, Tang H, Shi L, Jin L, Holmes E, Ding C, Zhu T, Zhang Y. Blood molecular markers associated with COVID-19 immunopathology and multi-organ damage. EMBO J. 2020 Dec 15; 39(24):e105896. doi: 10.15252/embj.2020105896.
2. Zhou B, Qi F, Wu F, Nie H, Song Y, Shao L, Han J, Wu Z, Saiyin H, Wei G, Wang P, Ni T, Qian F. Endogenous Retroviruses Derived Long Non-coding RNA Enhances Innate Immune Responses via De-repressing RELA Expression. mBio.2019 Jul 30; 10(4). pii: e00937-19.
3. Li P, Jin Y, Qi F, Wu F, Luo S, Cheng Y, Montgomery RR, Qian F. SIRT6 Acts as a Negative Regulator in Dengue Virus-Induced Inflammatory Response by Targeting the DNA Binding Domain of NF-κB p65. Front Cell Infect Microbiol. 2018; Apr 9; 8: 113.
4.Qian F, Wang X, Zhang L, Chen S, Piecychna M, Allore H, Bucala R, Fikrig E, Montgomery RR., Age-associated elevation in TLR5 leads to increased inflammatory responses in elderly. Aging Cell, 2012 Feb; 11(1):104-10.
5.Qian F, Wang X, Zhang L, Lin A, Zhao H, Fikrig E, Montgomery RR., Impaired interferon signaling in dendritic cells from older donors infected in vitro with West Nile virus. J Infect Dis. 2011 May 15; 203(10):1415-24.