教師基本信息:
姓名:陸豔
職稱:副研究員
電子郵箱:lueyan@fudan.edu.cn
辦公地點:複旦大學江灣校區生命科學樓A309
個人簡介:
女,副研究員,博士生導師。2006年作為直博生進入複旦大學學習,2012年獲複旦大學遺傳學博士學位,隨後進入中國科學院上海生命科學研究院從事研究工作,曆任助理研究員、副研究員。2020年進入複旦大學生命科學學院,任副研究員。長期從事群體遺傳學和基因組學相關研究,發表SCI論文40餘篇。近年來以第一作者和通訊作者(含共同)在Nature,Molecular Biology and Evolution, National Science Review, Cell Reports, iScience, Genome Biology, Science China Life Sciences等國際權威雜誌上發表多篇SCI研究性論文。入選上海市青年科技英才“揚帆計劃”,主持國家自然科學基金青年項目、麵上項目,任國家重點研發計劃課題負責人和子課題負責人,研究成果入選F1000,中國生物信息學十大科學進展、中國生物信息學十大數據庫、中國十大醫學科技新聞等。任Hereditas編委、Phenomics青年編委,上海人類學學會“分子人類學”專業委員會秘書長、常務委員。
1. 病原驅動的人類適應性演化
2. 亞洲特有病原的遺傳多樣性及其與宿主的共進化
3. 人群泛基因組參考圖譜構建及應用
4. 生物信息數據庫和分析平台
授課情況:
《基因組學》、《現代微生物專題》、《人類進化遺傳學》(本科生榮譽課程)、《專業英語》(生物信息)
招生專業
遺傳學、生物信息學、微生物學等
本課題組招收博後、研究生、本科生,請通過郵箱聯係我們。
課題組網站:https://pog.fudan.edu.cn/
代表性論文和論著
Xixian Ma#,Yan Lu#,*,Shuhua Xu*. Adaptive Evolution of Two Distinct Adaptive Haplotypes of Neanderthal Origin at the Immunoglobulin Heavy-chain Locus in East Asian and European Populations. Molecular Biology and Evolution.2024.41(7): msae147.
Yang Gao#, Xiaofei Yang#, Hao Chen#, Xinjiang Tan#, Zhaoqing Yang#, Lian Deng#, Baonan Wang, Shuang Kong,Songyang Li,Yuhang Cui, Chang Lei, Yimin Wang, Yuwen Pan, Sen Ma, Hao Sun, Xiaohan Zhao, Yingbing Shi, Ziyi Yang, Dongdong Wu, Shaoyuan Wu, Xingming Zhao, Binyin Shi, Li Jin, Zhibin Hu,Chinese Pangenome Consortium (CPC), Yan Lu*, Jiayou Chu*, Kai Ye*, Shuhua Xu*.A Pangenome Reference of 36 Chinese populations. Nature.2023.19(7968):112-121.
Qi Liu, Bo Xie, Yang Gao, Shuhua Xu* andYan Lu*. A protocol for applying low-coverage whole-genome sequencing data in structural variation studies. STAR Protocols.2023.4(3):102433.
Qi Liu, Ke Yang, Bo Xie, Yang Gao, Shuhua Xu*,Yan Lu*. Mapping Structural Variations in Haemaphysalis longicornis andRhipicephalus microplus Reveals Vector–Pathogen Adaptation, iScience, 2023
Yuwen Pan, Jia Wen, Zhilin Ning, Yuan Yuan, Xubing Liu, Yajun Yang, Yaqun Guan, Yan Lu*, Dolikun Mamatyusupu, Shuhua Xu*. Comparative genomic and transcriptomic analyses reveal the impacts of genetic admixture in Kazaks, Uyghurs, and Huis, Molecular Biology and Evolution, 2023
Zeshan Lin#,Yan Lu#, Guoliang Yu; Huajing Teng, Bao Wang, Yajun Yang, Qinglan Li, Zhongsheng Sun, Shuhua Xu*, Wen Wang*, Peng Tian*. Genome-wide DNA methylation landscape of four Chinese populations and epigenetic variation linked to Tibetan high-altitude adaptation, SCIENCE CHINA Life Sciences, 2023
Xueling Ge#,Yan Lu#, Shuanghui Chen#, Yang Gao, Lifeng Ma, Lijun Liu, Jiaojiao Liu, Xixian Ma, Longli Kang*, Shuhua Xu*. Genetic origins and adaptive evolution of the Deng people on the Tibetan Plateau. Molecular Biology and Evolution.2023.40(10):msad205.
Fang Luo, Wenbin Yang, Mingbo Yin, Xiaojin Mo, Yuhong Pang, Chengsong Sun, Bingkuan Zhu, Wei Zhang, Cun Yi, Zhidan Li, Jipeng Wang, Bin Xu, Zheng Feng, Yangyi Huang, Yan Lu*, Wei Hu*. A chromosome-level genome of the human blood fluke Schistosoma japonicum identifies the genomic basis of host-switching, Cell Reports, 2022, 39(1)
Yuwen Pan#, Chao Zhang#,Yan Lu#, Zhilin Ning, Dongsheng Lu, Yang Gao, Xiaohan Zhao, Yajun Yang, Yaqun Guan, Dolikun Mamatyusupu, Shuhua Xu. Genomic diversity and post-admixture adaptation in the Uyghurs, National Science Review, 2021, doi:10.1093/nsr/nwab