教師基本信息：
姓名：全哲學Zhe-Xue Quan
職稱：教授Professor
電子郵箱：quanzx@fudan.edu.cn
辦公地點：複旦大學生命科學學院 C305室
Room C305, School of Life Sciences, Fudan University
辦公電話：021-31246665
研究方向：
研究全程硝化菌（comammox）的生理生化特點以及其在生態係統中的作用；
深海微生物資源的挖掘；
人體皮膚微生物組研究；
開發新方法去追尋被“遺漏”的微生物。
Ecological characteristics of complete ammonia oxidizer (comammox)
Mining of deep sea microbial resources,
Human skin microbiome
Seeking of missed microbes with developed methods
個人簡介：
男，1973年出生，博士，教授。在北京大學化學係獲學士學位，在韓國科學技術院生物科學係獲博士學位。2005年開始在複旦大學生命科學學院任講師、副教授和教授。國外SCI雜誌PLoS ONE和Journal of Microbiology的編委，Frontiers in Microbiology的審稿編委；國家自然科學基金委重大研究項目“水圈微生物驅動地球元素循環的機製”專家組學術秘書。
Graduated Peking University and took Ph.D degree in Korea Advanced Institute of Science and Technology. Editorial board member of PLoS ONE and Journal of Microbiology, and review editor of Frontiers in Microbiology. Member of Teaching Community in Chinese Society of Microbiology,
授課情況：
微生物學（本科生專業必修課）
微生物分子生態學（本科生專業選修課）
微生物分子生態學（研究生選修課）
Microbiology
Microorganisms in Our Daily Life
Molecular Microbial Ecology
招生專業：
微生物學（學術碩士、學術博士）
生物與醫藥（工程碩士、工程博士）
Microbiology
代表性論文和論著：
全程硝化菌以及其它硝化相關微生物
Complete ammonia oxidizers (Comammox) and other Nitrifiers
1. Ru-Yi Zhang#, Yan-Ren Wang#, Ru-Long Liu, Sung-Keun Rhee, Guo-Ping Zhao, Zhe-Xue Quan* Metagenomic characterization of a novel non-ammonia-oxidizing Thaumarchaeota from hadal sediment. Microbiome. 12:7, 2024.
2. Kai Zhang, Hui-Feng Sun, You-Cai Kang, Ran Jiang, Yan-Ren Wang, Ru-Yi Zhang, Sheng Nan Zhang, Yang-Yang Li, Peng Li, Fan Yang, Sheng Zhou, Zhe-Xue Quan*. Comammox plays a functionally important role in the nitrification of rice paddy soil with different nitrogen fertilization levels. Appl Soil Ecol. 193, 105120, 2024.
4. Dan-Qi Wang, Cheng-Hao Zhou, Ming Nie, Ji-Dong Gu, Zhe-Xue Quan. Abundance and niche specificity of different types of complete ammonia oxidizers (comammox) in salt marshes covered by different plants. Sci Tot Environ. 768:144993, 2021.
5. Ran Jiang, Jian-Gong Wang, Ting Zhu, Bin Zou, Dan-Qi Wang, Sung-Keun Rhee, Dong An, Zhi-Yuan Ji and Zhe-Xue Quan*. Use of newly designed primers for quantification of complete ammonia-oxidizing (comammox) bacterial clades and strict nitrite oxidizers in the genus Nitrospira.Appl Environ Microbiol. 86:e01775, 2020.
6. Xia F, Wang J-G, Zhu T, Zou B, Rhee S-K, Quan Z-X*. Ubiquity and diversity of complete ammonia oxidizers (comammox). Appl Environ Microbiol. 84:e01390, 2018. （至2024年9月，被SCI雜誌他引160多次）
7. Jian-Gong Wang, Fei Xia, Jemaneh Zeleke, Bin Zou, Sung-Keun Rhee, and Zhe-Xue Quan∗. An improved protocol with a highly degenerate primer targeting copper-containing membrane-bound monooxygenase genes for community analysis of methane- and ammonia-oxidizing bacteria. FEMS Microbiol Ecol. 93(3), fiw244, 2018.
8.全哲學，追尋全程硝化菌之路:基因序列驅動的新功能微生物的發現，中國科學基金，5，479-484，2018.
9. Zhe-Xue Quan, Sung-Keun Rhee, Jian-E Zuo, Yang Yang, Jin-Woo Bae, Ja Ryeong Park, Sung-Taik Lee, Yong-Ha Park*. Diversity of ammonium-oxidizing bacteria in a granular sludge anaerobic ammonium-oxidizing (anammox) reactor. Environ Microbiol. 10, 3130-3139, 2008. (發現第五個厭氧氨氧化菌候選屬；至2024年9月，被SCI雜誌引用300多次)
人體皮膚微生物組
Human Skin Microbiome
10. Ting Zhu, Xing Liu, Fan-Qi Kong, Yuan-Yuan Duan, Alyson L. Yee, Madeline Kim, Carlos Galzote, Jack A. Gilbert, and Zhe-Xue Quan*. Age and mothers: potent influences of children’s skin microbiota, J Invest Derm. 139, 2497-2505, 2019. （同期有專家點評文章；被Faculty of 1000推薦）
11. Dan-Qi Wang†, Xi Li *,† , Ru-Yi Zhang, Chao Yuan, Bo Yan, Philippe Humbert and Zhe-Xue Quan* Effects of investigational moisturizers on the skin barrier and microbiome following exposure to environmental aggressors: A randomized clinical trial and ex vivo analysis.J Clinic Med. 12, 6078, 2023.
12. Yan-Ren Wang#, Ting Zhu#, Fan-Qi Kong, Yuan-Yuan Duan, Carlos Galzote, Zhe-Xue Quan* Infant mode of delivery shapes the skin mycobiome of prepubescent children. Microbiol Spectrum. 10 (5):e02267-22, 2020.
13. Ting Zhu, Yuan-Yuan Duan, Fan-Qi Kong, Carlos Galzote and Zhe-Xue Quan*. Dynamics of skin mycobiome in infants. Front Microbiol. 11: 1790, 2020.
14. Shi Ying, Dan-Ning Zeng, Liang Chi, Yuan Tan, Carlos Galzote, Cesar Cardona, Simon Lax, Jack Gilbert, Zhe-Xue Quan*. The influence of age and gender on skin-associated microbial communities in urban and rural human populations. PLoS One. 10, e0141842, 2015. （至2024年9月，被SCI雜誌引用170多次）
新類型微生物
Novel Microorganisms
15. Zhe-Xue Quan, Wan-Taeck Im. Fimbriimonadia. In Book: Bergey’s Manual of Systematics of Archaea and Bacteria. John Wiley & Sons, Inc. 2020.
16. W-T Im, Z-Y Hu, K-H Kim, S-K Rhee, H Meng, S-T Lee and Z-X Quan*. Description of Fimbriimonas ginsengisoli gen. nov., sp. nov. within the Fimbriimonadia class nov., of the phylum Armatimonadetes.Antonie van Leeuwenhoek J. 102, 307-317, 2012. （發現細菌新的綱）
17. Ru-Yi Zhang, Bin Zou, Yong-Wei Yan, Che Ok Jeon, Meng Li, Mingwei Cai, Zhe-Xue Quan*. Design of targeted primers based on 16S rRNA sequences in meta-transcriptomic datasets and identification of a novel taxonomic group in the Asgard archaea. BMC Microbiol. 20(1), 25, 2020.
18. Yong-Wei Yan, Bin Zou, Ting Zhu, Wael N. Hozzein, Zhe-Xue Quan*. Modified RNA-seq method for microbial community and diversity analysis using rRNA in different types of environmental samples. PLoS ONE. 12(10), e0186161, 2017.
19. X-R Li, Y Lv, H Meng, J-D Gu, Z-X Quan*. Analysis of microbial diversity by pyrosequencing the small-subunit ribosomal RNA without PCR amplification. Appl Microbiol Biotechnol. 98, 3777-3789, 2014.
20. D-P Mao, Q Zhou, C-Y Chen, Z-X Quan*. Coverage evaluation of universal bacterial primers using the metagenomic datasets. BMC Microbiol. 12, 66, 2012. （至2024年9月，被SCI雜誌引用150多次）